NISTFDA Workshop: Standards for Pathogen Detection via Next Generation Sequencing
نویسندگان
چکیده
The purpose of this NIST-FDA workshop was to seek input on defining reference materials, reference data and reference methods for assessing analytical sensitivity, specificity, and relative performance of NGS-based pathogen detection devices/assays. These reference materials will be critical in addressing the challenges associated with mixed pathogen detection in complex samples (i.e. clinical, environmental) using shotgun metagenomic sequencing and targeted resequencing (culture-independent diagnostics) approaches.
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